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19th International Workshop on Vascular Anomalies

сб., 05/05/2012 - 13:27 — Y.Y.Sergeev
16 июн 2012 - 00:00
19 июн 2012 - 23:59

Местоположение

Malmo
Sweden

The 19th International Workshop on Vascular Anomalies will take place in Malmo, Sweden, between the dates June 16-19, 2012.

Preliminary program:

 
Time Saturday June 16 , 2012
08.30-16.45
Basic course on the classification and treatment of Vascular Malformations and Tumours
A multidisciplinary approach
The basic course will cover the following topics:
Classification
Infantile hemangiomas
Capillary malformation - Port wine stain
Venous malformation
Lymphatic malformation
Arterial-/arteriovenous malformation
Histology
Psychology
Radiology
Interventional radiology
Surgery
Pediatric medicine
Laser treatment
18.00-20.00 Welcome reception at Malmö Opera
 
Time Sunday June 17, 2012
07.00
Registration
08.00 Opening ceremony & Welcome
08.15
Remembering Odile Enjolras
John Mulliken
08.25
Keynote speaker
"Mechanisms of growth and involution of infantile hemangioma"
Bjorn R. Olsen, MD, PhD
Hersey Professor of Cell Biology, Harvard Medical School
Professor of Developmental Biology and Dean for Research
Harvard School of Dental Medicine
08.55-10.17 Session I
Chair: Julie Powell, Paul Rieu
08.55 The Natural History of the Hepatic Rapidly Involuting Congenital Hemangioma
R Dawn Fevurly, Ann M Kulungowski, Emily R Christison-Lagay, Victor M Johnson, David Zurakowski, Ahmad I Alomari and Steven J Fishman
09.05 A Prospective study of Infantile Hemangiomas in Twins
M. Fernanda Greco, MD, Ilona J. Frieden, MD, Beth A. Drolet, MD, M. Rosa Cordisco, MD and Hemangioma Investigator Group --
09.13 Three-dimensional photograph registration in infantile hemangioma follow-up
Denise Hermans, Thomas Maal, Stefaan Bergé and Carine van der Vleuten
09.21 Early Growth of Infantile Hemangiomas: What Parents' Photographs Tell Us
Megha Tollefson and Ilona Frieden
09.31 Gastrointestinal Infantile Hemangiomas: A Retrospective Analysis
Ines Wu, Marilyn Liang, Victor Fox, Ahmad Alomari, John Mulliken and Steven Fishman
09.39 Increased risk for speech delay and dysphagia in patients with PHACE syndrome.
Kari Martin, Joan Arvedson, Beth Drolet, Dawn Siegel and Robert Chun
09.49 VINCRISTINE-ASPIRIN-TICLOPIDINE (VAT) THERAPY: NO MORTALITY IN VASCULAR TUMORS ASSOCIATED WITH KASABACH-MERRITT PHENOMENON IN THE LAST 15 YEARS
Israel Fernandez-Pineda, Juan Carlos Lopez-Gutierrez, Gloria Chocarro, Jose Bernabeu-Wittel and Gema Ramirez
09.57 Multidisciplinary consensus-driven treatment protocols for KHE and uniform diagnostic criteria for MLT
Yvonne Chiu, Denise Adams, Maria Garzon, Michael Kelly, Kelly Duffy and Beth Drolet
10.07 Sirolimus for the treatment of Kaposiform Hemangioendotheliomas/Tufted Angiomas
Denise M. Adams, Adrienne M. Hammill, Mary Sue Wentzel, Christine Minges, Rebecca Turner, Kristina Kruskamp, Carol Chute, Manish Patel, Carl Merrow, Belinda Dickie, Roshni Dasgupta, Ravi G. Elluru and Richard G. Azizkhan
10.17 Coffee
11.00-12.28 Session II
Chair: Beth Drolet, Michel Wassef
11.00
HEMANGIOL STUDY: the first world wide dose effect study concerning propranolol in infantile hemangiomas
Christine Léauté-Labrèze, Caroline Morgan and Jean-Jacques Voisard
11.10 Cardiovascular and Blood Glucose Parameters in Infants initiated on Propranolol for Treatment of Symptomatic Hemangiomas
Katherine Puttgen, Jeremy Schneider, Shetarra Walker, Bernard Cohen and Nancy Bauman
11.20 Expanding the therapeutic repertoire of infantile hemangiomas: Cohort blinded study of oral nadolol compared with propranolol
Elena Pope, Ajith Chakkittakandiyil, Irene Lara-Corrales, Ellen Maki, Bing Wu, Miriam Weinstein and Sylvain Baruchel
11.30 Efficacy of Acebutolol for the Treatment of Infantile Hemangiomas
Cameron Francis, Ashley Dunn, Ashley Karatsonyi, Sheila Nazarian-Mobin, Yvonne Gutierrez, Dean Anselmo and Andre Panossian
11.38 Topical betablockers for infantile hemangiomas are effective but systemically absorbed
Lisa Weibel, Helene Sophie Scheer, Marjam Barysch, Ingo Königs, Daniel Müller, Clemens Schiestl and Katharina Rentsch
11.48 Timolol maleate for infantile haemangiomas: preliminary results of an open label, prospective study
Kristina Semkova and Jana Kazandjieva
11.58 Propranolol suppresses angiogenesis through inhibiting the PI3K/Akt and ERK signaling pathways in endothelial cells
Jun Jia, Hai-Xiao Zou, Gang Chen and Yi-Fang Zhao
12.08 Propranolol causes functional changes in hemangioma stem cells and hemangioma endothelial cells
Alvin Wong, Krista Hardy, Alex Kitajewski, Carrie J. Shawber, Jan K. Kitajewski and June K. Wu
12.18 Treatment of Infantile Haemangioma with Captopril
Swee Tan, Tinte Itinteang, Darren Day, Clare O'Donnell, Jon Mathy and Philip Leadbitter
12.28 Lunch
13.30-14.28 Session III
chair: Gresham Richter, Francine Blei
13.30 Genome-Wide Association Study (GWAS) of Infantile Hemangiomas (IH): Functional Significance of Candidate Genes
Eun-Kyung M. Kwon, Dawn H. Siegel, Paula E. North, Yvonne E. Chiu, Elizabeth Worthey, Ulrich Broeckel and Beth Ann Drolet
13.38 p16INK4a-mediated Endothelial Cellular (EC) Senescence is a Fundamental Mechanism of Spontaneous Involution in Infantile Hemangioma (IH)
Qiuhui Yang, Valerie Salato, Kathrin Scherer, Hanae Onodera, Isabel DeAos, Barbara Wimpee, Milton Waner, Martin Mihm, Julie Tetzlaff and Paula North
13.48
Notch3 modulates cellular differentiation of hemangioma stem cells: A potential regulator of hemangioma stem cell fate
Krista Hardy, Alvin Wong, Carrie J. Shawber, Alex Kitajewski, Jan K. Kitajewski and June K. Wu
13.58 M2-polarized macrophages in infantile hemangiomas: correlation with promoted angiogenesis
Gang Chen, Feng-Qin Wang, Jun Jia, Zhi-Jun Sun and Yi-Fang Zhao
14.08 Pyogenic Granuloma, an Impaired Wound Healing Process Driven by VEGFR3 and the NO Pathway
Catherine Godfraind, Monica L. Calicchio and Harry P.W. Kozakewich
14.18
WT1 expression in the endothelial cells of vascular anomalies: A marker of vessel type and not of the tumor / malformation nature of the lesion, with special expression in IH and placenta.
Audrey Mansuet-Lupo, Elisabeth Sauvaget, Michel Borsik, Benoit Faucon, Didier Salvan, Annouk Bisdorff-Bresson and Michel Wassef
14.28-14.55 Coffee
14.55 Session IV
Chair: Ilona Frieden, Alex Barnacle
14.55 Dramatic efficacy of systemic steroids for the treatment of an aggressive orbital IH
Olivia Boccara, Valérie Dekeuleneer, Francis Brunelle, Sylvie Fraitag, Dominique Hamel-Teillac, Smail Hadj-Rabia and Christine Bodemer
15.10 Retroperitoneal RICH in a newborn baby with extensive arteriovenous shunting and acute heart failure.
Mats Cronqvist, Birgitta Ramgren, Agneta Troilius and Pär Gerwins
15.25-17.00 General Assembly
17.00-23.00 Traditional Swedish midsummer celebration at Kulturens Östarp

 
Time Monday June 18, 2012
08.00-09.30
Session V
Chair: Anthony Penington
08.00 Exome sequencing of suspected HHT patient reveals a novel RASA1 frameshift mutation: Clinical and diagnostic implications
Whitney Wooderchak-Donahue, Marc Singleton, Jamie McDonald, Mark Yandell and Pinar Bayrak-Toydemir
08.10 A xenograft animal Model of Human Arteriovenous Malformation
Fang Hou, Yuemeng Dai, Lisa Buckmiller, Chun-Yang Fan, Ali Saad, James Suen and Gresham Richter
08.20 Topological analysis of vessel structures in AVMs using 3D-CTA
Yuki Hata, Koichi Tomita, Ken Matsuda, Yasuo Sakai, Ko Hosokawa, Keigo Osuga and Shuichiro Uehara
08.30 Angioarchitecture of extracranial arteriovenous malformations: a vascular casting study
Xiaoxi Lin, Da Chen, Xiaojie Hu, Yunbo Jin, Wei Li, Gang Ma and Hui Chen
08.38 Arteriovenous malformations treatment strategies based on transarterial lung perfusion scintigraphy (TLPS)
Birute Vaisnyte, Donatas Vajauskas, Daiva Nevidomskyte, Nerijus Misonis, Darius Palionis, Marius Kurminas and Mindaugas Mataciunas
08.48 OPTIMIZATION AND PRECLINICAL TESTING OF NEW BIOCOMPATIBLE AND ADSORBABLE HYDROGEL MADE OF CHITOSAN AND SODIUM SOTRADECOL SULFATE
Gilles Soulez, Pascal Chabrot, Ahmed Fatimi, Jean-Michel Coutu, Saoussen Berrahmoune and Sophie Lerouge
08.56 Propranolol Therapy for AVMs
James Suen, Brad Hobbs and Gresham Richter
09.06 Propranolol as antiangiogenic candidate for the therapy of Hereditary Haemorragic Telangiectasia
Virginia Albiñana, Lucía Recio-Poveda, Roberto Zarrabeitia, Carmelo Bernabeu and Luisa María Botella
09.14 The HHT2 gene Activin Receptor-Like Kinase 1 (ALK1) is upregulated upon vascular injury via a transcriptional cooperation between Krüppel-like factor 6 (KLF6) and Sp1
Eva M. Garrido-Martín, Mercé Mercé Roquè, Laura Novensà, Mirko Tarocchi, Ursula E. Lee, Toru Suzuki, Scott L. Friedman, Luisa M. Botella and Carmelo Bernabeu
09.22 Thalidomide is an Effective Treatment for Arteriovenous Malformations associated with Pain, Ulceration and/or Bleeding
Laurence Boon, Vincent Qin, Liliane Marot, Frank Hammer, Anne Jeanjean, Philippe Clapuyt, Anne-Christine Bataille and Miikka Vikkula
09.30-10.20 Session VI
Chair: Wayne Yakes, Denise Adams
09.35 Sirolimus (Rapamune) - turning wrong into right?
Henrik Berlin, Cecilia Andersson and Carolin Freccero
09.50 AVM with multiple feeders in the left thigh treated with embolization of the superficial & deep femoral veins
Auh Whan Park, Alan Matsumoto, John Angle, Wael Saad, Saher Sabri, Kenneth Cherry and Ulku Turba
10.05 High Flow AVM of Pelvis with Congestive Cardiac Failure, Rectal Bleeding, and Limb Ischemia
Martin Simons and Kongteng Tan
10.20-11.00 Coffee and poster session I
11.00-13.17 Session VII
Chair: Patricia Burrow, Peter Berlien
11.00 The Natural History of Soft Tissue Hypertrophy, Bony Hypertrophy, and Nodule Formation in Patients with Untreated Head and Neck Capillary Malformation(CM)
Milton Waner, Ho Yun Chung, Teresa O and Aaron Fay
11.10 The Cynergy Multiplex Laser for vascular anomalies and for other skin lesions in children.
Samira Batul Syed, Maria Gnarra, Katherine Miler, Jane Linward and John Harper
11.20 Indocyanine green-augmented diode laser therapy of port wine stains
Annette Klein, Wolfgang Bäumler and Philipp Babilas
11.30 The surgical management of head and neck Capillary Malformations
Milton Waner, Teresa O, Ho Yun Chung, Catharina Poley and Aaron Fay
11.40
Capillary Venous Malformation of the Lower Extremities
Lily Uihlein, Marilyn Liang, Ahmad Alomari, Steven Fishman and John Mulliken
11.50 Vascular Malformations in Regional Overgrowth Syndromes
Peter Urban, Carsten M. Philipp, Margitta Poetke, Ute Müller, Hans-Peter Berlien and Sigrid Tinschert
11.58 Do we need a new classification of the venous anomalies in Klippel-Trenaunay syndrome? Correlation of the clinical, anatomic and hemodynamic characteristics
Ahmad Alomari and Raja Shaikh
12.06 Outcome of Surgical Debulking for Klippel-Trenaunay Syndrome
R Dawn Fevurly, Victor M Johnson and Steven J Fishman
12.14 GERMLINE MUTATIONS IN RASA1 ARE NOT FOUND IN PATIENTS WITH KLIPPEL-TRENAUNAY SYNDROME OR CAPILLARY MALFORMATION WITH OVERGROWTH
Nicole Revencu, Laurence Boon, Anne Dompmartin, Paul Rieu, Josee Dubois, Francesca Forzano, Annet van Hagen, Sarah Halbach, Alma Kuechler, Augusta Lachmeijer, Jyrki Lähde, Laura Russell, Kalle Simola and Miikka Vikkula
12.22 Clinical Characterization of Fibro-Adipose Vascular Anomaly (FAVA)
Ryan Arnold, Gulraiz Chaudry, Cindy Kerr, Raja Shaikh, Anna Lillis, Pradeep Govender, Samantha Spencer and Ahmad Alomari
12.32 Hematologic profile in CLOVES syndrome and risk of thromboembolism
Erin West, Rebecca Fevurly, Steven Fishman, Ahmad Alomari and Cameron Trenor
12.42 Wilms Tumor Screening is Necessary for Children with CLOVES Syndrome
R Dawn Fevurly, Arin K Greene, Cameron C Trenor III, Ahmad I Alomari, Denise Adams and Steven J Fishman
12.52 Role of Somatic Mutations in the Etiopathogenesis of the Maffucci Syndrome
Miikka Vikkula, Mustapha Amyere, John B. Mulliken, Anne Dompmartin, Odile Enjolras, Ilkka Kaitila, Pierre-Louis Docquier, Catherine Godfraind, Nisha Limaye and Laurence M. Boon
13.02 Unusual pulmonary arteriolar abnormalities in a patient with Klippel-Trenaunay syndrome
Benoit Ghaye, Laurence M Boon, Frank Hammer and Philippe Clapuyt
   
15.00-17.00 Optional activities in Malmö
19.30 Gala dinner at Malmö Opera
 
Time Tuesday June 19, 2012
07.30-08.30
Malmö in the morning: RUN, BIKE or WALK
09.10-11.00
Session VIII
Chair: John Mulliken, Carsten Philipp
09.10 Fasudil Decreases Lesion Burden in Murine Models of Cerebral Cavernous Malformations
Douglas Marchuk, David McDonald, Changbin Chi, Robert Shenkar, Rebecca Stockton, Feifei Liu, Mark Ginsberg and Issam Awad
09.20
Physiopathology of localized intravascular coagulopathy (LIC) associated to segmental venous malformations (VM): hyperfibrinolysis, hypocoagulability and presence of activated clotting factors
VITTORIA BARALDINI, PATRIZIA DELLA VALLE, FRANCESCA SAMPIETRO and ARMANDO D'ANGELO
09.28 Characterization of Venous Malformations in Blue Rubber Bleb Nevus Syndrome: The Dominant Lesion.
Anna Lillis, Gulraiz Chaudry, Steven Fishman, Cindy Kerr, Raja Shaikh and Ahmad Alomari
09.36 Identification of the cause of the Blue Rubber Bleb Nevus Syndrome
Miikka Vikkula, Julie Soblet, Nisha Limaye, Maria R. Cordisco, Anne Dompmartin, Odile Enjolras, Simon Holden, Alan D. Irvin, Christine Labrèze, Agustina Lanoel, Paul N. Rieu, Samira Syed, Carine J. Van der Vleuten, Rosemarie Watson, Steven J. Fishman, John B. Mulliken and Laurence M. Boon
09.46 Single Stage Removal of Localized Head and Neck Venous Malformations with Glue Embolization and Surgery
David Tieu, Nghia Vo, Basavaraj Ghodke and Jonathan Perkins
09.54 MRI of vascular anomalies: value of diffusion imaging
Josee Dubois, Françoise Rypens, Chantale Lapierre, Julie Powell, Catherine McCuaig and Gilles Soulez
10.04 Bleomycin induces endothelial mesenchymal transition via activation of Akt/mTOR pathway
Wei Zhang, Jian-Gang Ren and Yi-Fang Zhao
10.14 STS sclerotherapy for patients with venous malformation: Clinical discrepancy between patient-based and MRI-based evaluation.
Norimitsu Tanaka, Shuji Nagata, Toshi Abe, Yusuke Uchiyama, Naofumi Hayabuchi and Kensuke Kiyokawa
10.22 Severe Pulmonary Embolic Complications Of Ethanol Embolotherapy Of Vascular Anomalies
Robert Vogelzang
10.32 Prospective randomized evaluation of the treatment efficacy of ethanol 96% formulated in a gel and ethanol 98% solution in patients with VM
Sally Mitchell, Denis Herbreteau, Deborah Schwengel, Gina Robinson, Caroline Miklaszewski and Patrick Dupuy
10.42 Radiation Exposure during Interventional Radiology procedures for Vascular Malformations
James Suen, Eren Erdem, Lynn McGuire, Gresham Richter and Adewumi Amole
10.52 The 810-nm diode laser. A good wave as an alternative to superficial VMs' treatment. A preliminary report.
Gianni Vercellio, Giuseppe Carella, Vittorio Danesino and Maria Grazia Bordoni
11.00-11.45 Coffee
11.45-13.15 Session IX
Parallel session I
Laser surgery and IPL treatment of vascular malformations and tumours.		 Parallel session II
Interventional radiology
13.15-14.15 Lunch
14.15-15.19 Session X
Chair: Sally Mitchell
14.15 VEGFR3-driven Lymphangioblast Migration Requires MAPK-ERK Signaling
R Dawn Fevurly, Domenic Filingeri, Alexander Fye, Sean Hasso, Steven J Fishman and Joanne Chan
14.25 Gene array comparison of lymphatic malformation and human foreskin lymphatic endothelial cells
Tony Penington, Zerina Williams and Raminder Dhillon
14.35 A Novel Approach to the Identification of Candidate Genes in Patients with Lymphatic Malformations
Kelly Duffy, Craig Johnson, Jennifer Santoro and Ramani Ramchandran
14.45 Abnormal Flow Dynamics in the Central Conducting Lymphatics: Real-Time Illustration of Potential Etiology.
Ahmad Alomari
14.53 Sclerotherapy as a single-line treatment for orbital lymphatic malformations
Alex Barnacle, Eva Gajdosova and Yassir Abou-Rayyah
15.01 Clinical Applications of Protein Foams in the Treatment of Vascular Malformations
William Shiels
15.09 Efficacy of OK-432 sclerotherapy in treatment of lymphatic malformations: long-term follow up results
Annamaria Weitz-Tuoretmaa, Leo Keski-Nisula, Riitta Rautio, Jan Valkila, Harri Keski-Säntti and Jussi Laranne
15.19-16.48 Session XI
Chair: Gilles Soulez, Jochen Roessler
15.19 Ultrasound-assisted liposuction and pull-through technique for treatment of lymphatic malformations
Cameron Francis, Lily Tung, Ashley Karatsonyi, Dean Anselmo, Phillip Stanley and Andre Panossian
15.27
 The Difficult Airway in Patients with Vascular Anomalies of the Head and Neck: A Case Series of 238 Video Laryngoscopies using the GlideScope®
Robert Bolash, Franco Resta-Flarer, Jonathan Lesser, Keith Haller, Milton Waner and Teresa O
15.37 Treatment of massive tongue and cervical LMs with Sirolimus.
Emir Haxhija and Michael Höllwarth
15.47 Clinical Follow up of Six Patients with Complicated Vascular Anomalies treated with Sirolimus
Adrienne M. Hammill, Mary Sue Wentzel, Carol Chute, Manish Patel, Roshni Dasgupta, Richard G. Azizkhan and Denise M. Adams
15.55 Treating Lymphatic Bone Disease: Medical Therapy in Gorham Stout Disease and Generalized Lymphatic Anomaly
R Dawn Fevurly, Gulraiz Chaudry, Steven J Fishman and Cameron C Trenor III
16.05
Kaposiform Lymphangiomatosis: A New Entity Distinct from Generalized Lymphatic Anomaly, Kaposiform Hemangioendothelioma, Lymphedema-associated Angiosarcoma, and Lymphangioma-like Kaposi Sarcoma
Antonio R. Perez-Atayde, Stacy E. Croteau, Cameron C. Trenor III, Gulraiz Chaudry, Ahmad I. Alomari, John B. Mulliken, Steven J. Fishman and Harry P.W. Kozakewich
16.15 Lower Extremity Lymphedema Associated with Elevated Body Mass Index in Obese Patients
Arin Greene MD, MMSc, Reid Maclellan MD, Rafael Couto BA, Sumner Slavin MD and Frederick Grant MD
16.23 Mutations in KIF11 cause primary lymphedema
Miikka Vikkula, Antonella Mendola, Matthieu Schlögel, Arash Ghalamkarpour, Pia Ostergaard, Pradeep Vasudevan, Bart Loeys, Koen Devriendt, Thomy de Ravel, Maria Soller, Karen Fieggen, Mercedes Villanueva, Martin Bialer, Peter S. Mortimer, Sahar Mansour, Steve Jeffery, Amihood Singer, Nicole Revencu, Laurence M. Boon and Pascal Brouillard
16.33 Complex lymphatic venous malformation:Is there a role for rapamycin
Eulalia Baselga, Manuel de Juan, Silvia Bague, Juan Carlos Pernas, Nuria Pardo, Jorge Villalba, Ana Belen Cerezuelo, Alejandro Tomasello, Ruben Guerrero, Susana Lopez, Monica Paola Novoa, Mauricio Torres, Xavier Soria and Luis Puig
16.48-17.20 Sparkling refreshments
17.20-17.50 Closing and awards

More information can be found on the official site of the Congress.